Increase in Human Parvovirus B19 Activity in the U.S.

The CDC issued a Health Alert Network (HAN) Health Advisory to notify health care providers, public health authorities, and the public about current increases in human parvovirus B19 activity in the U.S. Parvovirus B19 is a seasonal respiratory virus that is transmitted through respiratory droplets by people with symptomatic or asymptomatic infection. In the first quarter of 2024, public health authorities in 14 European countries observed unusually high numbers of cases of parvovirus B19. Recently, CDC has received reports indicating increased parvovirus B19 activity in the U.S. Data include increased test positivity for parvovirus B19 in clinical specimens and pooled plasma from a large commercial laboratory, and reports of clusters of parvovirus B19-associated complications among pregnant people and people with sickle cell disease. See the full Health Advisory for more information, including recommendations for health care providers.

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